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Obst Lab - Lymphocyte Activation


obstResearch Topics

  • T cell activation and exhaustion
  • Interaction of T and B cells
  • Antigen processing and presentation
  • In vivo models of inducible gene expression



PD Dr. Reinhard Obst

phone: +49 (0)89 - 2180 75631

Photo: Jan Greune

T cells are a key component of adaptive immunity, our natural system of defence against pathogens like bacteria and viruses. When they recognize pathogens, massive changes in their physiology occur and they differentiate into effector cells equipped with the proper means for the pathogens' removal. We investigate how these changes are regulated and explore what happens in cases the pathogen does not get cleared but persists for extended periods of time. Read more...


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Scientific vita

since 2013 Lecturer Institute for Immunology, Biomedical Center, LMU Munich
since 2006 Group leader Institute for Immunology, Biomedical Center, LMU Munich
1998-2006 Postdoctoral researcher IGBMC Strasbourg, France, and Harvard Medical School, Boston, USA (C. Benoist and D. Mathis Labs)
1998 PhD in Biology University of Konstanz, Advisors: U. Krawinkel and H.-G. Rammensee, Tübingen