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Molecular Biology

All major functions of eukaryotic genomes – first an foremost the transcription of genes and the silencing of unscheduled activity and the recognition and repair of DNA damage – are governed by their organisation into chromatin. Chromatin structure is key to converting the genetic blueprint of an organism into a series of functionally diverse, cell-specific epigenomes. The groups of the Molecular Biology Division address various aspects of chromatin structure and epigenome function during cell growth and differentiation, organismic development and disease. On the one hand, chromatin structures are maintained dynamic and flexible to enable a cellular response to metabolic, physiologic and external signals. Other activities promote the assembly of lasting, heritable structures, which serve to organise chromosomes and define cellular identity. We are interested in how functional states derive from the interplay of those two opposing principles.

Peter Becker
- Director BMC -

Molecular Biology

Biomedical Center 
Großhaderner Strasse 9
82152 Planegg-Martinsried
+49 (0)89 2180 75427