Heissmeyer Lab - Post-transcriptional gene regulation in T cells
Immunology
Research Topics
- Post-transcriptional control of T cell differentiation
- Function of RNA-binding proteins and m6A RNA methylation
- Global analysis of binding Sites in the transcriptome
- Autoimmunity and anti-tumor immmunity
phone: +49 (0)89 - 2180 75629
vigo.heissmeyer@med.uni-muenchen.de
Photo: C. Olesinski / LMU
T lymphocytes require well-adjusted transcriptional and post-transcriptional gene expression programs to initiate immune responses against pathogens. Surprisingly, even in the absence of infections they similarly depend on active post-transcriptional gene regulation to remain silent and not cause damage to the body’s own tissues. Our work aims to decipher how RNA-binding proteins control T cell quiescence and shape activation, differentiation and effector functions. Read more...
Publications
https://orcid.org/0000-0002-2263-8545
Scientific vita
| Year | Function | Institute |
|---|---|---|
| since 2012 | Professor | Institute for Immunology, Biomedical Center, LMU Munich |
| since 2005 | Group leader | Research Unit Molecular Immune Regulation, Helmholtz Munich |
| 2001-2005 | Postdoctoral researcher | Rao Lab, Harvard Medical School, Boston, USA |
| 2000 | Postdoctoral researcher | Scheidereit Lab, Max Delbrück Center Berlin |
| 1999 | PhD in Biology | Freie Universität Berlin, Advisor: Claus Scheidereit |