Götz Lab - Neurogenesis
Physiological Genomics
Research Topics
- Neural stem cells
- Neurogenesis
- Glia-to-neuron reprogramming
- Neuronal repair
Photo: Jan Greune
We study the mechanisms of brain development and neurogenesis to understand basic novel mechanisms of neural stem cell self-renewal and differentiation and mechanisms of neuronal fate specification which we can then transfer aiming towards repair. Neurons are not replaced after injury or in neurodegenerative disease. We have therefore pioneered the approach to turn local glial cells in the adult mammalian brain into new neurons and now work on improving this conversion, examining the integration of the new neurons and targeting scar-forming glia for reprogramming to also alleviate scar-formation. Read more...
Publications
https://orcid.org/0000-0003-1551-9203
Scientific vita
| Year | Function | Institute |
|---|---|---|
| since 2011 | W3 Professorship | Dept. Physiological Genomics, Biomedical Center, LMU Munich |
| since 2004 | Chair of Physiological Genomics | Medical Faculty, LMU Munich |
| since 2004 | Director | Stem Cell Institute, GSF – since 01.01.2008: Helmholtz Zentrum München, Neuherberg-Munich |
| 1997-2003 | Group Leader | Max-Planck Institute of Neurobiology, Martinsried |
| 1997 | Scientist | Max-Planck Institute of Biophysical Chemistry, Göttingen |
| 1994-1996 | Postdoctoral Scientist | SmithKline Beecham Harlow, U.K |
| 1993-1994 | Postdoctoral Fellow | National Institute for Medical Research, London, U.K. |
| 1992 | PhD in Biology | Friedrich-Miescher Institute of the Max-Planck Society, Tübingen |