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Deindl Lab - Arteriogenesis

Cardiovascular Physiology and Pathophysiology

deindlResearch Topics

  • Arteriogenesis
  • Vascular biology
  • Innate immunity
  • Extracellular nucleic acids

Photo: Jan Greune

We investigate the molecular mechanisms of arteriogenesis, i.e. the growth of pre-existing arteriolar connections into functional bypasses. For our studies, we employ a murine hindlimb model. In detail, we are studying how increased shear stress, the trigger of arteriogenesis, is translated into biological signals, and how these signals are propagated within a cell as well as from cell to cell. Moreover, we are investigating the functional role of the innate immune system. Besides a variety of molecular and immunohistological analyses, we perform in vitro studies. Read more...


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Scientific vita

since 2006 Group leader Cardiovascular Physiology and Pathophysiology/Walter Brendel Centre for Experimental Medicine (WBex), LMU Munich
2001-2006 Scientist Medical clinic 1, University Hospital, LMU Munich
1997-2001 Scientist Max Planck Institute for Heart and Lung Research, Bad Nauheim
1995-1996 Postdoctoral researcher Max Planck Institute for Heart and Lung Research, Bad Nauheim
1994 PhD in Biology ZMBH, University of Heidelberg, Advisor: Heinz Schaller