Kawakami Lab - Live imaging of CNS autoimmunity
Clinical Neuroimmunology
Research Topics
- Autoimmunity
- Intravital imaging
- T cells
Photo: Jan Greune
Our research focusses on autoreactive, CNS-specific T cells that induce inflammation in the brain. The use of intravital two-photon microscopy and functional fluorescent markers in EAE, an animal model for Multiple Sclerosis, allows us to visualize not only T-cell activation but also migration and interactions with other cell types in real-time. These obtained parameters promote our understanding of how the fate of autoreactive T cells is influenced by their environment and vice versa. Read more...
Publications
https://orcid.org/0000-0001-7693-3489
Scientific vita
| Year | Function | Institute |
|---|---|---|
| since 2011 | Group leader | Institute of Clinical Neuroimmunology, University Hospital and Biomedical Center, LMU Munich |
| 2003-2011 | Group leader | Department of Neuroimmunology, Max Planck Institute of Neurobiology |
| 2001-2002 | Postdoctoral researcher | Department of Neuroimmunology, Max-Planck Institute of Neurobiology |
| 2001 | PhD in Pharmaceutical Sciences | Osaka University, Japan, Advisor: H. Yamamoto |