Biomedical Center Munich

Language Selection

Breadcrumb Navigation


Rupp Lab - Developmental Epigenetics

Molecular Biology

ruppResearch Topics

  • Chromatin-based regulation of vertebrate development
  • Histone modification profiling and mass spectrometry
  • Cell cycle and embryonic differentiation
  • Developmental programs and gene regulatory networks


Prof. Dr. Ralph Rupp

phone: +49 (0)89 - 2180 75438

Photo: Jan Greune

We study chromatin-based mechanisms which guide developmental transitions in Xenopus embryos. Currently, we focus on molecular mechanisms which establish the histone modification landscape during vertebrate embryogenesis. We hold special expertise in identifying signaling pathways and transcriptional programs which underlie embryonic phenotypes brought about by perturbing chromatin modifying enzymes. The techniques we apply include classical embryonic experimentation, various gain- and loss-of-function analyses, confocal microscopy and state-of-the-art genome-wide approaches (RNA-/ChIP-Seq, Mass Spectrometry).  Read more...


ORCID logo

Scientific vita

since 2000 Associate professor Dept. Molecular Biology, Biomedical Center, LMU Munich
1993-2000 Independent group leader Friedrich Miescher Laboratory, MPG Tübingen
1990-1993 Postdoctoral researcher Fred Hutchinson Cancer Research Center, Seattle, WA, USA
1989 PhD in Biology University of Heidelberg