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Liebscher Lab - Circuit mechanisms of neurodegenerative disorders

Clinical Neuroimmunology

liebscherResearch Topics

  • Cellular and circuit mechanisms of Amyotrophic Lateral Sclerosis
  • Circuit dysfunction in anti-NMDAR autoimmune encephalitis
  • Astrocyte physiology and pathophysiology in vivo
  • Sensorimotor integration using two-photon imaging in behaving mice

Dr. Sabine Liebscher

phone: +49 (0)89 - 2180 71659
sabine.liebscher@med.uni-muenchen.de

Photo: Jan Greune

Our main aim is to unravel the cellular and circuit mechanisms that contribute to CNS disorders in order to identify therapeutically amenable circuit elements as novel strategies to combat these disorders. To this end we employ cutting-edge in vivo imaging to chronically study the structure and function of neurons and glia cells at single cell/synapse resolution in behaving mice. These in vivo studies are complemented by a variety of additional methods, such as circuit mapping, chemogenetic manipulation, region- and cell type-specific transcriptomic and proteomic analyses etc. Read more...

Publications

ORCID logo https://orcid.org/0000-0001-5633-8981

Scientific vita

YearFunctionInstitute
since 2017 Emmy Noether Group leader Institute of Clinical Neuroimmunology, University Hospital and Biomedical Center, LMU Munich
since 2014 Clinician scientist group leader, Resident in Neurology Institute of Clinical Neuroimmunology, University Hospital and Biomedical Center, LMU Munich
2008-2014 PhD studies Max Planck Institute of Neurobiology, Martinsried, and Dept. Biochemistry, LMU Munich
2007-2008 Research assistant Rockefeller University, New York City, USA
2007 MD Technical University of Dresden