Biomedical Center Munich

Language Selection

Breadcrumb Navigation


Klein Lab - Thymus Function


kleinResearch Topics

  • T cell repertoire selection
  • Central T cell tolerance
  • Regulatory T cells



Prof. Dr. Ludger Klein

phone: +49 (0)89 - 2180 75427

Photo: Jan Greune

We aim to elucidate the cellular interactions and molecular pathways that orchestrate the generation of a 'useful' T cell repertoire and imprint self-tolerance. To do so, we employ genetically manipulated mouse models that allow us to dissect T-cell-intrinsic and -extrinsic determinants shaping the T cell pool during repertoire selection in the thymus. Read more...


ORCID logo

Scientific vita

since 2007 Associate professor Institute for Immunology, Biomedical Center, LMU Munich
2001-2007 Group leader Research Institute of Molecular Pathology (IMP), Vienna, Austria
1999-2001 Postdoctoral researcher von Boehmer Lab, Dana-Farber-Cancer Institute, Boston, USA
1997-1999 Postdoctoral researcher Kyewski Lab, German Cancer Research Institute (DKFZ), Heidelberg
1993-1997 PhD in Biology University of Cologne / DKFZ Heidelberg, Advisors: Howard and Kyewski