Klein Lab - Thymus Function
Immunology
Research Topics
- T cell repertoire selection
- Central T cell tolerance
- Regulatory T cells
We aim to elucidate the cellular interactions and molecular pathways that orchestrate the generation of a 'useful' T cell repertoire and imprint self-tolerance. To do so, we employ genetically manipulated mouse models that allow us to dissect T-cell-intrinsic and -extrinsic determinants shaping the T cell pool during repertoire selection in the thymus. Read more...
Publications
https://orcid.org/0000-0003-2054-071X
Scientific vita
| Year | Function | Institute |
|---|---|---|
| since 2007 | Associate professor | Institute for Immunology, Biomedical Center, LMU Munich |
| 2001-2007 | Group leader | Research Institute of Molecular Pathology (IMP), Vienna, Austria |
| 1999-2001 | Postdoctoral researcher | von Boehmer Lab, Dana-Farber-Cancer Institute, Boston, USA |
| 1997-1999 | Postdoctoral researcher | Kyewski Lab, German Cancer Research Institute (DKFZ), Heidelberg |
| 1993-1997 | PhD in Biology | University of Cologne / DKFZ Heidelberg, Advisors: Howard and Kyewski |