Dormann Lab - Molecular Neurodegeneration
Cell Biology - Anatomy III
Research Topics
- Molecular mechanisms of neurodegeneration
- Nucleocytoplasmic transport
- Phase separation
- Protein/RNA biochemistry and cell culture
We are interested in RNA-binding proteins that are mislocalized and aggregated in the neurodegenerative disorders ALS (amyotrophic lateral sclerosis) and FTD (Frontotemporal dementia). Using biochemical and cell biological approaches, we investigate how nucleocytoplasmic transport, phase separation and post-translational modifications of disease-linked RNA-binding proteins are normally regulated, how these processes are disturbed in disease and how these defects contribute to neurodegeneration. Read more...
Publications
https://orcid.org/0000-0002-9260-2775
Scientific vita
| Year | Function | Institute |
|---|---|---|
| since 2014 | Group leader | Dept. Cell Biology, Biomedical Center, LMU Munich |
| 2007-2014 | Postdoctoral researcher | Christian Haass lab, Adolf-Butenandt-Institute/Metabolic Biochemistry, LMU Munich |
| 2003-2007 | PhD in Cell Biology/Immunology | Rockefeller University, New York, USA, Advisor: C. Münz |