Biomedical Center Munich

Language Selection

Breadcrumb Navigation


Dormann Lab - Molecular Neurodegeneration

Cell Biology - Anatomy III

dormannResearch Topics

  • Molecular mechanisms of neurodegeneration
  • Nucleocytoplasmic transport
  • Phase separation
  • Protein/RNA biochemistry and cell culture

We are interested in RNA-binding proteins that are mislocalized and aggregated in the neurodegenerative disorders ALS (amyotrophic lateral sclerosis) and FTD (Frontotemporal dementia). Using biochemical and cell biological approaches, we investigate how nucleocytoplasmic transport, phase separation and post-translational modifications of disease-linked RNA-binding proteins are normally regulated, how these processes are disturbed in disease and how these defects contribute to neurodegeneration. Read more...


ORCID logo

Scientific vita

since 2014 Group leader Dept. Cell Biology, Biomedical Center, LMU Munich
2007-2014 Postdoctoral researcher Christian Haass lab, Adolf-Butenandt-Institute/Metabolic Biochemistry, LMU Munich
2003-2007 PhD in Cell Biology/Immunology Rockefeller University, New York, USA, Advisor: C. Münz