Becker Lab - Chromatin Dynamics
Molecular Biology
Research Topics
- Chromosome-wide gene regulation
- Long, non-coding roX RNA
- Variant histone dynamics
- Factor cooperativity in chromosomal locus control
Photo: Jan Greune
We explore the principles and mechanisms of regulation of genome functions through chromatin organisation. We are particularly interested in ATP-dependent nucleosome ‘remodeling’ machines and in the mechanisms of transcriptional fine-tuning during dosage compensation. Our model organism is Drosophila melanogaster. We employ a wide range of methods from biochemistry, genomics, cell biology, reverse genetics and collaborate with colleagues on structural aspects. Our methodological specialty is the reconstitution of chromatin structure and function on a genome-wide scale in cell-free systems (genome-wide biochemistry). Read more...
Publications
https://orcid.org/0000-0001-7186-0372
Scientific vita
| Year | Function | Institute |
|---|---|---|
| since 1999 | Professor of Molecular Biology | Dept. Molecular Biology, Biomedical Center, LMU Munich |
| 1991-1999 | Group leader | European Molecular Biology Laboratory, Heidelberg |
| 1988-1991 | Postdoctoral researcher | Carl Wu Lab, NIH, National Cancer Institute, USA |
| 1987 | PhD in Biology | University of Heidelberg, Advisor: Günther Schütz |
Downloads
- becker_cv (75 KByte)